อ.ทนพญ.ดร.กัญญารัตน์ ถึงอินทร์ (Dr.Kanyarat Thueng-in, PhD)

General Information

    Name: Kanyarat Thueng-in
    
Rank:  Lecturer & Researcher   
    
E-mail: kanyarat.th@sut.ac.th  
    
Tel:    (+66) 44 223 986

 

 

Academic Credentials:

  • Ph.D. (Biomedical Science), 2009, Thamasart University, Prathumthani, Thailand.
  • B.Sc. (Medical Technology), 2001, Naresuan University, Pitsanulok, Thailand.
Course Training
  • Genetic Engineering, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
  • Molecular Microbiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
  • Molecular Immunology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
Research Interests:

  • Molecular Immunology
  • Genetic Engineering
  • Molecular Microbiology

Selected Publications:

  1. Kaewpitoon SJ, Ponphimai S, Petdee P, Thueng-in K, Khiaowichit J, Meererksom T, Wakkhuwatapong P, Bukkhunthod P, Leng M, Namhong T, Taweepakdeechot A, Yardcharoen N, Panithanang B, Srithongklang W, Panpimanmas S, Kaewpitoon N. The prevalence of intestinal helminthic infection in rural villagers, Northeastern Thailand. Trop Biomed. accepted
  2. Bukkhunthod P, Meererksom T, Pechdee P, Ponphimai S, Khiaowichit J, Kaewpitoon N, Thueng-in K, Leng M, Namhong T, Taweepakdeechot A, Yardcharoen N, Srithongklang W, Wakhuwathapong P, Keeratibharat N, Kaewpitoon SJ. Animation as Supplementary Learning Material about Carcinogenic Liver Fluke in Classes for Primary Schoolchildren. J Canc Educ. 2018 Oct 5. doi:10.1007/s13187-018-1434-5.
  3. Glab-Ampai K, Chulanetra M, Malik AA, Juntadech T, Thanongsaksrikul J, Srimanote P, Thueng-In K, Sookrung N, Tongtawe P, Chaicumpa W. Publisher Correction: Human single chain-transbodies that bound to domain-I of non-structural protein 5A (NS5A) of hepatitis C virus. Sci Rep. 2018 Apr 25;8(1):6787. doi: 10.1038/s41598-018-24856-4. PubMed PMID: 29693654; PubMed Central PMCID: PMC5915417
  4. Jittavisutthikul S, Seesuay W, Thanongsaksrikul J, Thueng-In K, Srimanote P, Werner RG, Chaicumpa W. Human Transbodies to HCV NS3/4A Protease Inhibit Viral Replication and Restore Host Innate Immunity. Front Immunol. 2016 Aug 26;7:318. doi: 10.3389/fimmu.2016.00318. eCollection 2016. PubMed PMID: 27617013; PubMed Central PMCID: PMC4999588.
  5. Glab-Ampai K, Malik AA, Chulanetra M, Thanongsaksrikul J, Thueng-In K, Srimanote P, Tongtawe P, Chaicumpa W. Inhibition of HCV replication by humanized-single domain transbodies to NS4B. Biochem Biophys Res Commun. 2016 Aug 5;476(4):654-664. doi: 10.1016/j.bbrc.2016.05.109. Epub 2016 May 27. PubMed PMID:27240954.
  6. Jittavisutthikul S, Thanongsaksrikul J, Thueng-In K, Chulanetra M, Srimanote P, Seesuay W, Malik AA, Chaicumpa W. Humanized-VHH transbodies that inhibit HCV protease and replication. Viruses. 2015 Apr 20;7(4):2030-56. doi:10.3390/v7042030. PubMed PMID: 25903832; PubMed Central PMCID: PMC4411689.
  7. Dong-din-on F, Songserm T, Pissawong T, Srimanote P, Thanongsaksrikul J, Thueng-in K, Moonjit P, Lertwatcharasarakul P, Seesuay W, Chaicumpa W. Cell penetrable human scFv specific to middle domain of matrix protein-1 protects mice from lethal influenza. Viruses. 2015 Jan 14;7(1):154-79. doi: 10.3390/v7010154. PubMed PMID: 25594836; PubMed Central PMCID: PMC4306832.
  8. Thueng-in K, Thanongsaksrikul J, Jittavisutthikul S, Seesuay W, Chulanetra M, Sakolvaree Y, Srimanote P, Chaicumpa W. Interference of HCV replication by cell penetrable human monoclonal scFv specific to NS5B polymerase. MAbs. 2014;6(5):1327-39. doi: 10.4161/mabs.29978. PubMed PMID: 25517317; PubMed Central PMCID: PMC4622650.
  9. Danpaiboon W, Reamtong O, Sookrung N, Seesuay W, Sakolvaree Y, Thanongsaksrikul J, Dong-din-on F, Srimanote P, Thueng-in K, Chaicumpa W. Ophiophagus hannah venom: proteome, components bound by Naja kaouthia antivenin and neutralization by N. kaouthia neurotoxin-specific human ScFv. Toxins (Basel). 2014 May 13;6(5):1526-58. doi: 10.3390/toxins6051526. PubMed PMID: 24828754; PubMed Central PMCID: PMC4052251.
  10. Phalaphol A, Thueng-In K, Thanongsaksrikul J, Poungpair O, Bangphoomi K, Sookrung N, Srimanote P, Chaicumpa W. Humanized-VH/VHH that inhibit HCV replication by interfering with the virus helicase activity. J Virol Methods. 2013 Dec;194(1-2):289-99. doi: 10.1016/j.jviromet.2013.08.032. Epub 2013 Sep 12. PubMed PMID: 24036073.
  11. Yodsheewan R, Maneewatch S, Srimanote P, Thueng-In K, Songserm T, Dong-Din-On F, Bangphoomi K, Sookrung N, Choowongkomon K, Chaicumpa W. Human monoclonal ScFv specific to NS1 protein inhibits replication of influenza viruses across types and subtypes. Antiviral Res. 2013 Oct;100(1):226-37. doi:10.1016/j.antiviral.2013.07.019. Epub 2013 Aug 6. PubMed PMID: 23928258.
  12. Pissawong T, Maneewatch S, Thueng-In K, Srimanote P, Dong-din-on F, Thanongsaksrikul J, Songserm T, Tongtawe P, Bangphoomi K, Chaicumpa W. Human monoclonal ScFv that bind to different functional domains of M2 and inhibit H5N1 influenza virus replication. Virol J. 2013 May 14;10:148. doi:10.1186/1743-422X-10-148. PubMed PMID: 23672256; PubMed Central PMCID:PMC3660209.
  13. Thueng-in K, Thanongsaksrikul J, Srimanote P, Bangphoomi K, Poungpair O, Maneewatch S, Choowongkomon K, Chaicumpa W. Cell penetrable humanized-VH/V(H)H that inhibit RNA dependent RNA polymerase (NS5B) of HCV. PLoS One. 2012;7(11):e49254. doi: 10.1371/journal.pone.0049254. Epub 2012 Nov 8. PubMed PMID: 23145135; PubMed Central PMCID: PMC3493538.
  14. Chavanayarn C, Thanongsaksrikul J, Thueng-In K, Bangphoomi K, Sookrung N, Chaicumpa W. Humanized-single domain antibodies (VH/VHH) that bound specifically to Naja kaouthia phospholipase A2 and neutralized the enzymatic activity. Toxins (Basel). 2012 Jul;4(7):554-67. doi: 10.3390/toxins4070554. Epub 2012 Jul 19. PubMed PMID: 22852068; PubMed Central PMCID: PMC3407892.
  15. Thueng-in K, Maneewatch S, Srimanote P, Songserm T, Tapchaisri P, Sookrung N, Tongtawe P, Channarong S, Chaicumpa W. Heterosubtypic immunity to influenza mediated by liposome adjuvanted H5N1 recombinant protein vaccines. Vaccine. 2010 Sep 24;28(41):6765-77. doi: 10.1016/j.vaccine.2010.07.065. Epub 2010 Aug 3. PubMed PMID: 20688037.
  16. Poungpair O, Chaicumpa W, Kulkeaw K, Maneewatch S, Thueng-in K, Srimanote P, Tongtawe P, Songserm T, Lekcharoensuk P, Tapchaisri P. Human single chain monoclonal antibody that recognizes matrix protein of heterologous influenza A virus subtypes. J Virol Methods. 2009 Jul;159(1):105-11. doi:10.1016/j.jviromet.2009.03.010. Epub 2009 Mar 20. PubMed PMID: 19442853.
  17. Maneewatch S, Thanongsaksrikul J, Songserm T, Thueng-In K, Kulkeaw K, Thathaisong U, Srimanote P, Tongtawe P, Tapchaisri P, Chaicumpa W. Human single-chain antibodies that neutralize homologous and heterologous strains and clades of influenza A virus subtype H5N1. Antivir Ther. 2009;14(2):221-30. PubMed PMID: 19430097.
  18. Thathaisong U, Maneewatch S, Kulkeaw K, Thueng-In K, Poungpair O, Srimanote P, Songserm T, Tongtawe P, Tapchaisri P, Chaicumpa W. Human monoclonal single chain antibodies (HuScFv) that bind to the polymerase proteins of influenza A virus. Asian Pac J Allergy Immunol. 2008 Mar;26(1):23-35. PubMed PMID: 18595527.